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Below is a list of the most relevant publications of the lab. For a complete list of publications check my Google Scholar or Orcid profiles. 

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Pulschen, A. A., Fernandes, A. Z., Cunha, A. F., Sastre, D. E., Matsuguma, B. E., & Gueiros-Filho, F. J. (2021). Many birds with one stone: targeting the (p) ppGpp signaling pathway of bacteria to improve antimicrobial therapy. Biophysical Reviews, 13: 1039–1051. LINK

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Yu Y., Dempwolff F., Oshiro R.T., Gueiros-Filho F.J., Jacobson S.C., Kearns D.B. (2021). The Division Defect of a Bacillus subtilis minD noc Double Mutant Can Be Suppressed by Spx-Dependent and Spx-Independent Mechanisms. J Bacteriol. 203(18):e0024921. doi: 10.1128/JB.00249-21. Epub 2021 Aug 20. LINK

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Yu, Y., Zhou, J., Gueiros-Filho, F. J., Kearns, D. B., & Jacobson, S. C. (2021). Noc Corrals Migration of FtsZ Protofilaments during Cytokinesis in Bacillus subtilis. mBio, 12(1), e02964-20. https://doi.org/10.1128/mBio.02964-20 LINK

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Sastre, D. E., Pulschen, A. A., Basso, L., Benites Pariente, J. S., Marques Netto, C., Machinandiarena, F., Albanesi, D., Navarro, M., de Mendoza, D., & Gueiros-Filho, F. J. (2020). The phosphatidic acid pathway enzyme PlsX plays both catalytic and channeling roles in bacterial phospholipid synthesis. The Journal of Biological Chemistry, 295(7), 2148–2159. https://doi.org/10.1074/jbc.RA119.011147 LINK

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Sastre, D. E., Basso, L., Trastoy, B., Cifuente, J. O., Contreras, X., Gueiros-Filho, F., de Mendoza, D., Navarro, M., & Guerin, M. E. (2020). Membrane fluidity adjusts the insertion of the transacylase PlsX to regulate phospholipid biosynthesis in Gram-positive bacteria. The Journal of Biological Chemistry, 295(7), 2136–2147. https://doi.org/10.1074/jbc.RA119.011122 - LINK

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Rodrigues-Costa, F., Slivinski, J., Ióca, L. P., Bertonha, A. F., de Felício, R., Cunha, M., da Mata Madeira, P. V., Cauz, A., Trindade, D. M., Freire, V. F., Ropke, C. D., Gales, A., Brocchi, M., Ferreira, A. G., Gueiros-Filho, F., Trivella, D., Berlinck, R., & Dessen, A. (2020). Merulinic acid C overcomes gentamicin resistance in Enterococcus faecium. Bioorganic Chemistry, 100, 103921. https://doi.org/10.1016/j.bioorg.2020.103921 - LINK

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Cauz, A., Carretero, G., Saraiva, G., Park, P., Mortara, L., Cuccovia, I. M., Brocchi, M., & Gueiros-Filho, F. J. (2019). Violacein Targets the Cytoplasmic Membrane of Bacteria. ACS infectious diseases, 5(4), 539–549. https://doi.org/10.1021/acsinfecdis.8b00245 - LINK

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Pulschen, A. A., Sastre, D. E., Machinandiarena, F., Crotta Asis, A., Albanesi, D., de Mendoza, D., & Gueiros-Filho, F. J. (2017). The stringent response plays a key role in Bacillus subtilis survival of fatty acid starvation. Molecular Microbiology, 103(4), 698–712. https://doi.org/10.1111/mmi.13582 - LINK

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Sastre, D.E., Bisson-Filho, A., de Mendoza, D. and Gueiros-Filho, F. (2016). Revisiting the cell biology of the acyl-ACP:phosphate transacylase PlsX suggests that the phospholipid synthesis and cell division machineries are not coupled in Bacillus subtilis. Mol. Microbiol. Jan 27. doi: 10.1111/mmi.13337. [Epub ahead of print]

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Bisson-Filho, A.W., Discola, K. F., Castellen, P., Blasios, V., Martins, A, Sforça, M., Garcia, W., Zeri, A.C.M. Erickson, H.P., Dessen, A.and Gueiros-Filho, F.J. (2015) FtsZ filament capping by MciZ, a developmental regulator of bacterial division. Proc. Natl. Acad. USA 112:E2130-E21388.

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Blasios. V., Bisson-Filho, A.W., Castellen, P., Nogueira, M.L.C., Bettini, J., Portugal, R., Zeri, A.C.M. and Gueiros-Filho, F.J. (2013) Genetic and biochemical characterization of the MinC-FtsZ interaction in Bacillus subtilis. PLoS One, 8(4):e60690. 

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Wagner-Herman, J. K., Bernard, R., Dunne, R., Bisson-Filho, A. W., Kumar, K., Nguyen, T., Mulcahy, L., Koullias, J., Gueiros-Filho, F. J., & Rudner, D. Z. (2012). RefZ facilitates the switch from medial to polar division during spore formation in Bacillus subtilis. Journal of Bacteriology, 194(17), 4608–4618. https://doi.org/10.1128/JB.00378-12 - LINK

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dos Santos, V. T., Bisson-Filho, A. W., & Gueiros-Filho, F. J. (2012). DivIVA-mediated polar localization of ComN, a posttranscriptional regulator of Bacillus subtilis. Journal of Bacteriology, 194(14), 3661–3669. https://doi.org/10.1128/JB.05879-11 - LINK

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Tavares, J. R., de Souza, R. F., Meira, G. L., & Gueiros-Filho, F. J. (2008). Cytological characterization of YpsB, a novel component of the Bacillus subtilis divisome. Journal of Bacteriology, 190(21), 7096–7107. https://doi.org/10.1128/JB.00064-08 - LINK

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de Souza, R. F., Anantharaman, V., de Souza, S. J., Aravind, L., & Gueiros-Filho, F. J. (2008). AMIN domains have a predicted role in localization of diverse periplasmic protein complexes. Bioinformatics (Oxford, England), 24(21), 2423–2426. https://doi.org/10.1093/bioinformatics/btn449 - LINK

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